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Main project Synthesis and characterisation of protease inhibitors identified in a high-throughput screen Main activities Synthesis of peptide protease inhibitors by solid phase peptide synthesis (SPPS) General SPPS workflow using Fmoc chemistry (deprotection, coupling, cleavage) Cyclic peptide synthesis using a cyclative release strategy on disulfide-linked resin Purification of peptides using reverse-phase HPLC Analysis and confirmation of synthesised peptides using LC-MS Confirming synthesised peptides as hits of previous high-throughput screening Measuring IC50 values using a functional binding assay against thrombin to quantify inhibitory performance of previously identified hits

• Synthesis of new hypervalent iodine reagents. • Working in moisture- and oxygen-free conditions using Schlenk line techniques. • Work with potentially hazardous chemicals and learned good practices in their use and storage. • Learned importance of teamwork and maintaining a clean and organised work environment.

• Helping in sample preparation and formation of metal foams using Hydrogen evolution reaction. • Analyzing the formed metal foam structure using electron microscopy. • Electrochemically reducing CO2 to alcohols and alkanes and analyzing the products using gas chromatography. • Studying the efficiency of different metal foams in the application of reduction of carbon dioxide.