Benjamin Ostendorf
Max Eder group leader at Charité University Medicine
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Career: 5
Max Eder group leader
Charité University Medicine
On-site
Attending physician (Funktionsoberarzt)
Charité University Medicine Berlin (Dpt. of Hematology/Oncology/Tumor Immunology)
On-site
Resident and Internal Medicine specialist
Charité University Medicine Berlin (Dpt. of Hematology/Oncology/Tumor Immunology)
Berlin, Berlin, DE
Postdoc
The Rockefeller University (Tavazoie Lab)
New York, New York, US · On-site
Resident
Charité University Medicine Berlin (Dpt. of Hematology/Oncology/Tumor Immunology)
Berlin, Berlin, DE
Publications: 29
Cancer Research
Journal ArticleShugaku Takeda, Subhasree Sridhar, Daniel Schefer, Celia Andreu-Agullo, Pui C. Lo, Minhee Lee, Robert Busby, David M. Darst, Anne Assmus, Suresh Anaganti, Nils Halberg, Benjamin N. Ostendorf, Ivo C. Lorenz, Sohail F. Tavazoie, Masoud F. Tavazoie, Isabel Kurth
Liver-X-receptor agonism enhances T cell priming and activation to promote anti-tumor immunity
Journal of Experimental Medicine
Journal ArticleBenjamin N. Ostendorf, Jonathan G. Goldstein, Shuang Liu, Foster C. Gonsalves, Jana Bilanovic, Mathias Yuan, Ji-Young Kim, Christopher Rouya, Masoud Tavazoie, Sohail F. Tavazoie
BMC cancer
Journal ArticleSiegel R, Dittrich L, Plewe J, Denecke T, Leonhardi J, Tannapfel A, Reinacher-Schick A, Raschzok N, Sauer IM, Lauscher J, Lorenzen S, Götze T, Jelas I, Stahler A, Kurreck A, Ballhausen A, Ostendorf BN, Haase O, Pratschke J, Stintzing S, Modest DP
BEscreen: a versatile toolkit to design base editing libraries
Nucleic Acids Research
Journal ArticlePhilipp G Schneider, Shuang Liu, Lars Bullinger, Benjamin N Ostendorf
Common hereditary variants of the APOE gene and posttransplant outcome in acute myeloid leukemia.
Blood
Journal ArticleRonnacker J, Grau M, Klasmeier M, Klesse C, Baldauf H, Abert S, Berdel AF, Füsser FT, Sandmann S, Albring J, Reicherts C, Call S, Marx J, Floeth M, Eßeling E, Kolloch L, Berning P, Scheller A, Wethmar K, Schmidt H, Schlüter B, Berdel WE, Ostendorf BN, Tavazoie SF, Mikesch JH, Lenz G, Fleischhauer K, Schetelig J, Stelljes M, Schliemann C
Neuronal substance P drives metastasis through an extracellular RNA–TLR7 axis
Nature
Journal ArticleVeena Padmanaban, Isabel Keller, Ethan S. Seltzer, Benjamin N. Ostendorf, Zachary Kerner, Sohail F. Tavazoie
Recapitulating the tumor microenvironment in a dish, one cell type at a time.
Cell Reports Methods
Journal ArticleOstendorf BN
Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
Cancer Research
Journal ArticleNneoma Adaku, Benjamin N. Ostendorf, Wenbin Mei, Sohail F. Tavazoie
Nneoma Adaku, Benjamin N. Ostendorf, Wenbin Mei, Sohail F. Tavazoie
Common human genetic variants of APOE impact murine COVID-19 mortality
Nature
Journal ArticleBenjamin N. Ostendorf, Mira A. Patel, Jana Bilanovic, H.-Heinrich Hoffmann, Sebastian E. Carrasco, Charles M. Rice, Sohail F. Tavazoie
Apolipoprotein E2 Promotes Melanoma Growth, Metastasis, and Protein Synthesis via the LRP1 Receptor
Nneoma Adaku, Benjamin N. Ostendorf, Sohail F. Tavazoie
Developmental Cell
Journal ArticleMoy RH, Nguyen A, Loo JM, Yamaguchi N, Kajba CM, Santhanam B, Ostendorf BN, Wu YG, Tavazoie S, Tavazoie SF
Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells.
Cell metabolism
Journal ArticleZhu XG, Chudnovskiy A, Baudrier L, Prizer B, Liu Y, Ostendorf BN, Yamaguchi N, Arab A, Tavora B, Timson R, Heissel S, de Stanchina E, Molina H, Birsoy K
Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis
Nature
Journal ArticleBernardo Tavora, Tobias Mederer, Kai J. Wessel, Simon Ruffing, Mahan Sadjadi, Marc Missmahl, Benjamin N. Ostendorf, Xuhang Liu, Ji-Young Kim, Olav Olsen, Alana L. Welm, Hani Goodarzi, Sohail F. Tavazoie
Common germline variants of the human APOE gene modulate melanoma progression and survival
Nature Medicine
Journal ArticleBenjamin N. Ostendorf, Jana Bilanovic, Nneoma Adaku, Kimia N. Tafreshian, Bernardo Tavora, Roger D. Vaughan, Sohail F. Tavazoie
Autophagy Suppresses Breast Cancer Metastasis.
Developmental cell
Journal ArticleOstendorf BN, Tavazoie SF
Apoe genotyping in cancer prognostics and treatment
World Intellectual Property Organization (WIPO)
PatentTavazoie SF, Ostendorf BN, Tavazoie M, Gonsalves F
Germline genetic determination of cancer progression and survival
Benjamin N. Ostendorf, Kimia N. Tafreshian, Nneoma Adaku, Jana Bilanovic, Bernardo Tavora, Sohail F. Tavazoie
PLOS ONE
Journal ArticleBenjamin N. Ostendorf, Konradin Metze, Eva Flenner, Anne Flörcken, Jörg Westermann
LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer.
Cell
Journal ArticleTavazoie MF, Pollack I, Tanqueco R, Ostendorf BN, Reis BS, Gonsalves FC, Kurth I, Andreu-Agullo C, Derbyshire ML, Posada J, Takeda S, Tafreshian KN, Tavazoie SF
[Flow-cytometric immunophenotyping in clinical diagnostics].
Deutsche medizinische Wochenschrift (1946)
Journal ArticleFlörcken A, Takvorian A, Singh A, Gerhardt A, Ostendorf BN, Dörken B, Pezzutto A, Westermann J
Severe radiotoxicity in an allogeneic transplant recipient with a heterozygous ATM mutation.
Ostendorf BN, Terwey TH, Hemmati PG, Böhmer D, Pleyer U, Arnold R
Association between low uric acid levels and acute graft-versus-host disease.
Ostendorf BN, Blau O, Uharek L, Blau IW, Penack O
BCR-ABL Mutation-Guided Therapy for CML Blast Crisis: A Case Report.
Ostendorf BN, Nogai H, Baldus CD, Burmeister T, Arnold R
Ostendorf BN, le Coutre P, Kim TD, Quintás-Cardama A
Ostendorf BN, Jehn CF, Vuong LG, Nogai H, Hemmati PG, Gebauer B, Penack O, Blau IW, Anagnostopoulos I, Arnold R
Gödel M, Ostendorf BN, Baumer J, Weber K, Huber TB
Human staphylococcus intermedius infection in a patient with postradiation changes
Infectious Diseases in Clinical Practice
Journal ArticleOstendorf, B.N., Oehler, R.L., Greene, J.N.
Education: 3
The Rockefeller University
PhD, Systems Cancer Biology
University of Freiburg
Dr. med., Molecular Nephrology
University of Freiburg
MD, Medical School
Oct 2004 - Jun 2011
University of Freiburg
MD, Medical School
Clinical electives at University of South Florida (Tampa, USA), Queen Mary University (London, UK), and Mount Sinai School of Medicine (New York City, USA.
Awards: 2
- Jun 2025
Advanced Clinician Scientist Scholarship
German Society of Internal Medicine
- Jan 2022
Digital Clinician Scientist
Berlin Institute of Health
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