#  (@chrglstr.eurosky.social)

Profile: https://sifa.id/p/chrglstr.eurosky.social
Headline: MSc Student in Molecular and Biological Chemistry, EPFL, Switzerland

## About

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## Career

- **Master's project 1b in chemical biology (28 day project) at Laboratory of Therapeutic Proteins and Peptides, EPFL)** (Feb 2025 - Jun 2025)
  On-site
  Main project
  
  Synthesis and characterisation of protease inhibitors identified in a high-throughput screen
  
  Main activities
  
  Synthesis of peptide protease inhibitors by solid phase peptide synthesis (SPPS)
  
  General SPPS workflow using Fmoc chemistry (deprotection, coupling, cleavage)
  
  Cyclic peptide synthesis using a cyclative release strategy on disulfide-linked resin
  
  Purification of peptides using reverse-phase HPLC
  
  Analysis and confirmation of synthesised peptides using LC-MS
  
  Confirming synthesised peptides as hits of previous high-throughput screening
  
  Measuring IC50 values using a functional binding assay against thrombin to quantify inhibitory performance of previously identified hits
- **Master's project 1a in organic chemistry at Laboratory of Catalysis and Organic Synthesis, EPFL** (Aug 2024)
  • Synthesis of new hypervalent iodine reagents.
  • Working in moisture- and oxygen-free conditions using Schlenk line techniques.
  • Work with potentially hazardous chemicals and learned good practices in their use and storage.
  • Learned importance of teamwork and maintaining a clean and organised work environment.
- **Research Intern in electrochemistry at Interfacial Electrochemistry group, university of Bern** (Sep 2019)
  • Helping in sample preparation and formation of metal foams using Hydrogen evolution reaction.
  • Analyzing the formed metal foam structure using electron microscopy.
  • Electrochemically reducing CO2 to alcohols and alkanes and analyzing the products using gas chromatography.
  • Studying the efficiency of different metal foams in the application of reduction of carbon dioxide.

## Education

- **EPFL** — Master of Science - MSC, Molecular and biological chemistry (Sep 2024 - Jul 2026)
- **EPFL** — Bachelor of Science - BSC, Chemistry and chemical engineering (Sep 2020 - Jul 2024)

## Languages

- German (native)
- Romanian (native)
- English (full professional)
- French (professional working)

## Links

- LinkedIn: https://www.linkedin.com/in/christian-balea-986bb4268/